It is increasingly understood that personalised medicine that takes these factors into account achieves superior results than “one-size-fits-all” approaches, which may ignore, for example, individual risk of ischaemia or propensity to bleed with antithrombotics. 2Ī variety of individual factors and circumstances other than clinical presentation and treatment type contribute to determining the outcome of CAD. Guideline-directed medical therapy and revascularisation using percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) are the main treatment strategies across the spectrum of CAD. unstable angina, non-ST-elevation MI and ST-elevation myocardial infarction ). chronic angina pectoris) to acute coronary syndromes (ACS), which encompass a variety of clinical scenarios (e.g. 1 Based on clinical presentation and prognosis, CAD spans from stable presentations (e.g. Patients with TIMI score > 4 were more likely to have significant three vessel CAD and LMS versus those with TIMI risk score 4 should be referred for early invasive coronary evaluation to derive clinical benefit.Although a combination of multiple strategies to prevent and treat coronary artery disease (CAD) has led to a relative reduction in cardiovascular mortality over recent decades, CAD remains the greatest cause of morbidity and mortality worldwide.
The extent of CAD was evaluated on angiography and significant CAD was defined as ≥ 70% stenosis in any one of the three major epicardial vessels and ≥50% in LMS.Results : Among 100 patients with UA/NSTEMI, 82% of patients have one or more risk factors and only 18%of patients lacked any of 4 conventional risk factors.Smoking is the most common risk factor in male patients while diabetes mellitus and dyslipidemia are common among female patients, and all these results are statistically significant.There were 64 % patients with TIMI score 4 (high TIMI risk score). The TIMI risk score was stratified on seven standard variables. Extensive epidemiological research has established cigarette smoking, diabetes, hyperlipidemia, and hypertension as independent risk factors for CADObjective: To determine the prevalence of the 4 conventional risk factors(cigarette smoking, diabetes, hyperlipidemia, and hypertension) among patients with CAD and to determine the correlation of Thrombolysis in Myocardial Infarction (TIMI) risk score with the extent of coronary artery disease (CAD) in patients with unstable angina /non ST elevation myocardial infarction (UA/NSTEMI).Methods: We conducted a descriptive study among 100 patients admitted with UA/NSTEMI to three major cardiac centers in Iraq: Iraqi Centre for Heart Disease ,Ibn- Al-Bitar Hospital for cardiac surgery and Al -Nasyria Cardiac Centre from January 2010 to January 2o11.Frequency of each conventional risk factors and number of conventional risk factors present among patients with CAD, compared between men and women and by age are estimated at study entry.
Background: Appreciation of the crucial role of risk factors in the development of coronary artery disease (CAD) is one of the most significant advances in the understanding of this important disease.
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